Knoxville, MD

Knoxville sits in Frederick, Maryland, and is covered by 1 ZIP code tabulation area. Across those ZIPs, an estimated 4,610 people live, work, and commute. Demographic and housing figures come from the U.S. Census Bureau's American Community Survey 5-Year Estimates (2018–2022).

Each ZIP code in Knoxville has its own character. Some are dense and walkable; others are exurban or rural, with single-digit households per square mile. The list below lets you compare the basic shape of each one — population, income, and home value — before clicking through to the full neighborhood profile.

Across the city overall, the typical owner-occupied home is valued near $338,000 and median asking rent runs around $1,688 per month. Median household income hovers around $103,081. These are averages of ZIP-level medians and will read differently depending on which neighborhood you actually settle in — which is precisely what the per-ZIP pages are for.

ZIP codes in Knoxville

ZIP	County	Population	Median income	Median home value
21758	Frederick	4,610	$103,081	$338,000

Thinking about relocating to Knoxville?

A few practical considerations as you evaluate the move:

• Pick the ZIP, not just the city. Median income, school assignments, walkability and crime patterns can vary dramatically between neighboring ZIPs in the same city. Use the per-ZIP pages to compare.
• Compare housing math honestly. The median home value here is $338,000, and median rent is $1,688. At current mortgage rates, that often makes renting the more flexible option for the first 12–24 months while you learn the neighborhoods.
• Verify the commute. Drive your prospective work or school route at peak time — Google Maps optimistic estimates rarely match what locals actually experience.
• Check the boring stuff. Property tax rates, HOA dues, flood-zone designation, and homeowner's insurance availability are easier to research before you sign than after.